SLC39A10 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC39A10.
Immunogen
A synthetic peptide corresponding to 17 amino acids near internal region of human SLC39A10.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody will not cross-react with the zinc transporter ZIP11.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SLC39A10 in human spleen tissue lysate with SLC39A10 polyclonal antibody (Cat # PAB16690) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of SLC39A10 in human spleen tissue with SLC39A10 polyclonal antibody (Cat # PAB16690) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC39A10
Entrez GeneID
57181Protein Accession#
EAW70116Gene Name
SLC39A10
Gene Alias
DKFZp781L10106, LZT-Hs2, MGC126565, MGC138428
Gene Description
solute carrier family 39 (zinc transporter), member 10
Omim ID
608733Gene Ontology
HyperlinkGene Summary
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM
Other Designations
solute carrier family 39 (metal ion transporter), member 10
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Interactome
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Disease
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Publication Reference
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Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.
Kagara N, Tanaka N, Noguchi S, Hirano T.
Cancer Science 2007 May; 98(5):692.
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Upregulation of Slc39a10 gene expression in response to thyroid hormones in intestine and kidney.
Pawan K, Neeraj S, Sandeep K, Kanta Ratho R, Rajendra P.
Biochimica et Biophysica Acta 2007 Feb; 1769(2):117.
Application:IF, WB-Ti, Rat, Rat kidney, intestine .
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Molecular cloning and functional characterization of novel zinc transporter rZip10 (Slc39a10) involved in zinc uptake across rat renal brush-border membrane.
Kaler P, Prasad R.
American Journal of Physiology. Renal Physiology 2007 Jan; 292(1):F217.
Application:WB-Tr, Pig, LLC-PK1-Ve, LLC-PK1-Zip10 cells.
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Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.
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