CRMP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of CRMP1 in rat brain tissue lysate with CRMP1 polyclonal antibody (Cat # PAB16686) at (A) 1 and (B) 2 ug/mL .
Immunohistochemistry
Immunohistochemistry of CRMP1 in mouse brain tissue with CRMP1 polyclonal antibody (Cat # PAB16686) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CRMP1.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human CRMP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CRMP1 in rat brain tissue lysate with CRMP1 polyclonal antibody (Cat # PAB16686) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of CRMP1 in mouse brain tissue with CRMP1 polyclonal antibody (Cat # PAB16686) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — CRMP1
Entrez GeneID
1400Protein Accession#
AAH07613Gene Name
CRMP1
Gene Alias
DPYSL1, DRP-1, DRP1
Gene Description
collapsin response mediator protein 1
Omim ID
602462Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
dihydropyrimidinase related protein-1|dihydropyrimidinase-like 1
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Interactome
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Disease
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Publication Reference
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Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons.
Quach TT, Duchemin AM, Rogemond V, Aguera M, Honnorat J, Belin MF, Kolattukudy PE.
Molecular and Cellular Neurosciences 2004 Mar; 25(3):433.
Application：Func, WB, Chicken, Chicken embryos.
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Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders.
Charrier E, Reibel S, Rogemond V, Aguera M, Thomasset N, Honnorat J.
Molecular Neurobiology 2003 Aug; 28(1):51.
Application：WB-Ti, Human, Human brains.
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Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus.
Cameron HA, McKay RD.
The Journal of Comparative Neurology 2001 Jul; 435(4):406.
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Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons.
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