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GLE1 polyclonal antibody

  • Catalog # : PAB16679
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GLE1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus 15 amino acids of human GLE1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of GLE1 in mouse brain tissue lysate with GLE1 polyclonal antibody (Cat # PAB16679) at (A) 1 and (B) 2 ug/mL .
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemistry of GLE1 in mouse brain tissue with GLE1 polyclonal antibody (Cat # PAB16679) at 2.5 ug/mL .
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2733
  • Gene Name:
  • GLE1
  • Gene Alias:
  • GLE1L,LCCS,LCCS1,hGLE1
  • Gene Description:
  • GLE1 RNA export mediator homolog (yeast)
  • Gene Summary:
  • This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • GLE1 RNA export mediator homolog,GLE1 RNA export mediator-like,GLE1-like, RNA export mediator,OTTHUMP00000022280,OTTHUMP00000022281
  • Related Disease
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