TFB1M polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
TFB1M polyclonal antibody (Cat # PAB16639) (0.3 ug/mL) staining of A-431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TFB1M.
Immunogen
A synthetic peptide corresponding to human TFB1M.
Sequence
C-ELKRRKSKNEEKE
Host
Goat
Theoretical MW (kDa)
39.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
TFB1M polyclonal antibody (Cat # PAB16639) (0.3 ug/mL) staining of A-431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TFB1M
Entrez GeneID
51106Protein Accession#
NP_057104.2Gene Name
TFB1M
Gene Alias
CGI-75, CGI75, mtTFB, mtTFB1
Gene Description
transcription factor B1, mitochondrial
Omim ID
607033Gene Ontology
HyperlinkGene Summary
The transcription of genes from mitochondrial DNA requires a mitochondrial RNA polymerase (see POLRMT, MIM 601778) and a DNA-binding transcription factor (see TFAM, MIM 600438). Transcription factor B1 (TFB1M) is a part of this transcription complex.[supplied by OMIM
Other Designations
OTTHUMP00000017473|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1|homolog of yeast mitochondrial transcription factor B|mitochondrial 12S rRNA dimethylase 1
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Interactome
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Disease
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Publication Reference
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Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease.
Sanchez-Ferrero E, Coto E, Blazquez M, Ribacoba R, Guisasola LM, Salvador C, Alvarez V.
Parkinsonism & Related Disorders 2009 Jul; 15(6):468.
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Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease.
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