FERMT3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FERMT3.
Immunogen
A synthetic peptide corresponding to human FERMT3.
Sequence
C-ERARGEELDED
Host
Goat
Theoretical MW (kDa)
75.4
Reactivity
Human
Specificity
This antibody is expected to recognize both isoforms (NP_113659.3, NP_848537.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
FERMT3 polyclonal antibody (Cat # PAB16638) (1 ug/mL) staining of human peripheral blood mononucleocytes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FERMT3
Entrez GeneID
83706Protein Accession#
NP_113659.3;NP_848537.1Gene Name
FERMT3
Gene Alias
KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2, URP2SF
Gene Description
fermitin family homolog 3 (Drosophila)
Omim ID
607901Gene Ontology
HyperlinkOther Designations
UNC-112 related protein 2|fermitin family homolog 3|kindlin 3|kindlin-3
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Interactome
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Publication Reference
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Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.
Svensson L, Howarth K, McDowall A, Patzak I, Evans R, Ussar S, Moser M, Metin A, Fried M, Tomlinson I, Hogg N.
Nature Medicine 2008 Feb; 47(2):521.
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Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.
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