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Last updated: 2017/7/23

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GGCX polyclonal antibody

  • Catalog # : PAB16633
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GGCX.
  • Immunogen:
  • A synthetic peptide corresponding to human GGCX.
  • Sequence:
  • C-PPESNPDPVHSE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 87.6, 81
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • GGCX polyclonal antibody (Cat # PAB16633) (0.3 ug/mL) staining of human muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2677
  • Protein Accession#:
  • NP_000812.2;NP_001135741.1
  • Gene Name:
  • GGCX
  • Gene Alias:
  • FLJ26629,VKCFD1
  • Gene Description:
  • gamma-glutamyl carboxylase
  • Gene Summary:
  • This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • vitamin K-dependent gamma-carboxylase
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