Rabbit polyclonal antibody raised against synthetic protein of CD8A.
Immunogen:
Synthetic protein corresponding to CD8A.
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Form:
Lyophilized
Purification:
Protein G purification
Recommend Usage:
ELISA (1-2 ug/mL) Immunohistochemistry (2-10 ug/mL) Western Blot (2-10 ug/mL) The optimal working dilution should be determined by the end user.
Storage Buffer:
Lyophilized from PBS, pH 7.4.
Storage Instruction:
Store at -20°C on dry atmosphere. After reconstitution with PBS pH 7.4 or other diluents (such as distilled water), store at 2-8°C for one month, or at -20°C for six months without detectable loss of activity. Aliquot to avoid repeated freezing and thawing.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq