JPH4 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of JPH4 in 293 cell lysate with JPH4 polyclonal antibody (Cat # PAB16595) at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry
Immunohistochemistry of JPH4 in human brain tissue with JPH4 polyclonal antibody (Cat # PAB16595) at 2.5 ug/mL .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of JPH4.
Immunogen
A synthetic peptide corresponding to C-terminus 16 amino acids of human JPH4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of JPH4 in 293 cell lysate with JPH4 polyclonal antibody (Cat # PAB16595) at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.Immunohistochemistry
Immunohistochemistry of JPH4 in human brain tissue with JPH4 polyclonal antibody (Cat # PAB16595) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
-
Gene Info — JPH4
Entrez GeneID
84502Protein Accession#
AAH55429Gene Name
JPH4
Gene Alias
FLJ34253, JPHL1, KIAA1831, hJP-4
Gene Description
junctophilin 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000027957|junctophilin like 1|type I transmembrane protein
-
Interactome
-
Publication Reference
-
Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.
Kakizawa S, Kishimoto Y, Hashimoto K, Miyazaki T, Furutani K, Shimizu H, Fukaya M, Nishi M, Sakagami H, Ikeda A, Kondo H, Kano M, Watanabe M, Iino M, Takeshima H.
The EMBO Journal 2007 Mar; 26(7):1924.
Application：WB-Ti, Mouse, Mouse cerebellum.
-
Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.
Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, Saito SY, Watanabe M, Kondo H, Yawo H, Fukunaga K, Takeshima H.
PNAS 2006 Jun; 103(28):10811.
-
Coexpression of junctophilin type 3 and type 4 in brain.
Nishi M, Sakagami H, Komazaki S, Kondo H, Takeshima H.
Brain Research. Molecular Brain Research 2003 Oct; 118(1-2):102.
-
Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com