IL34 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL34.
Immunogen
A synthetic peptide corresponding to internal region 13 amino acids of human IL34.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of IL34 in human brain tissue lysate with IL34 polyclonal antibody (Cat # PAB16574) at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL34
Entrez GeneID
146433Protein Accession#
ACD13474Gene Name
IL34
Gene Alias
C16orf77, IL-34, MGC34647
Gene Description
interleukin 34
Gene Ontology
HyperlinkGene Summary
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM
Other Designations
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Interactome
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Publication Reference
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IL-34 is a Treg-specific cytokine and mediates transplant tolerance.
Bezie S, Picarda E, Ossart J, Tesson L, Usal C, Renaudin K, Anegon I, Guillonneau C.
The Journal of Clinical Investigation 2015 Oct; 125(10):3952.
Application:Flow Cyt, Human, Rat, T cells.
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Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.
Lin H, Lee E, Hestir K, Leo C, Huang M, Bosch E, Halenbeck R, Wu G, Zhou A, Behrens D, Hollenbaugh D, Linnemann T, Qin M, Wong J, Chu K, Doberstein SK, Williams LT.
Science 2008 May; 320(5877):807.
Application:Flow Cyt, Human, Human monocytes, PBMCs.
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IL-34 is a Treg-specific cytokine and mediates transplant tolerance.
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