DISP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DISP2.
Immunogen
A synthetic peptide corresponding to C-terminus 19 amino acids of human DISP2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of DISP2 in rat brain tissue lysate with DISP2 polyclonal antibody (Cat # PAB16566) at (A) 1 and (B) 2 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — DISP2
Entrez GeneID
85455Protein Accession#
A7MBM2Gene Name
DISP2
Gene Alias
DISPB, DKFZp547N223, HsT16908, KIAA1742
Gene Description
dispatched homolog 2 (Drosophila)
Omim ID
607503Gene Ontology
HyperlinkGene Summary
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq
Other Designations
dispatched B
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Publication Reference
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Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites.
Li N, Flynt AS, Kim HR, Solnica-Krezel L, Patton JG.
Nucleic Acids Research 2008 Aug; 36(13):4277.
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Hedgehog signaling pathway and gastric cancer.
Katoh Y, Katoh M.
Cancer Biology & Therapy 2005 Oct; 4(10):1050.
Application:IHC, WB, Human, Human gastric cancer.
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Identification and characterization of DISP3 gene in silico.
Katoh Y, Katoh M.
International Journal of Oncology 2005 Feb; 26(2):551.
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Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites.
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