ALDH3A2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ALDH3A2.
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human ALDH3A2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ALDH3A2 in mouse liver lysate with ALDH3A2 polyclonal antibody (Cat # PAB16546) at (Lane 1) 1 and (Lane 2) 2 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — ALDH3A2
Entrez GeneID
224Protein Accession#
NP_001026976Gene Name
ALDH3A2
Gene Alias
ALDH10, DKFZp686E23276, FALDH, FLJ20851, SLS
Gene Description
aldehyde dehydrogenase 3 family, member A2
Gene Ontology
HyperlinkGene Summary
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000065801|aldehyde dehydrogenase 10|aldehyde dehydrogenase 3A2|fatty aldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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Publication Reference
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Sjogren-Larsson syndrome: molecular genetics and biochemical pathogenesis of fatty aldehyde dehydrogenase deficiency.
Rizzo WB.
Molecular Genetics and Metabolism 2007 Jan; 90(1):1.
Application:WB, Human, Human fibroblasts, liver, Rat liver.
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Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease.
Vasiliou V, Pappa A.
Pharmacology 2000 Sep; 61(3):192.
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Sjogren-Larsson syndrome: molecular genetics and biochemical pathogenesis of fatty aldehyde dehydrogenase deficiency.
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