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Last updated: 2016/12/4
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STAT6 polyclonal antibody

  • Catalog # : PAB16538
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of STAT6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 808-826 of human STAT6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Researchers are encouraged to optimize dilution for their specific testing. human STAT6 is an 847 amino acid protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunofluorescence (5 ug/mL)
    Immunocytochemistry (5 ug/mL)
    Western Blot (0.25-0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of STAT6 in Jurkat cell lysate in the (Lane 1) absence and (Lane 2) presence of immunizing peptide, and (Lane 3) Raw cell lysate using STAT6 polyclonal antibody (Cat # PAB16538) at 0.25 ug/mL .
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical analysis of STAT6 in formalin-fixed Jurkat cells using an isotype control (top) and STAT6 polyclonal antibody (Cat # PAB16538) (bottom) at 5 ug/mL .
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 6778
  • Gene Name:
  • STAT6
  • Gene Alias:
  • D12S1644,IL-4-STAT,STAT6B,STAT6C
  • Gene Description:
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
  • Other Designations:
  • STAT, interleukin4-induced,signal transducer and activator of transcription 6,transcription factor IL-4 STAT
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