PDE11A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDE11A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human PDE11A.
Host
Rabbit
Reactivity
Bovine, Chicken, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebra fish
Specificity
Internal domain of human.
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human testis with PDE11A polyclonal antibody (Cat # PAB16443). -
Gene Info — PDE11A
Entrez GeneID
50940Protein Accession#
Q9HCR9Gene Name
PDE11A
Gene Alias
FLJ23693, MGC133355, MGC133356, PPNAD2
Gene Description
phosphodiesterase 11A
Gene Ontology
HyperlinkGene Summary
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cAMP and cGMP cyclic nucleotide phosphodiesterase 11A|cyclic nucleotide phosphodiesterase 11A|dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
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Interactome
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Disease
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