SGK3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SGK3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human SGK3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
N-terminal domain of human.
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human pancreas (islet) with SGK3 polyclonal antibody (Cat # PAB16431). -
Gene Info — SGK3
Entrez GeneID
23678Protein Accession#
Q96BR1Gene Name
SGK3
Gene Alias
CISK, DKFZp781N0293, SGK2, SGKL
Gene Description
serum/glucocorticoid regulated kinase family, member 3
Omim ID
607591Gene Ontology
HyperlinkGene Summary
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
cytokine-independent survival kinase|serum/glucocorticoid regulated kinase 3|serum/glucocorticoid regulated kinase-like
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Interactome
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Publication Reference
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SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
Qing-Qing Dong, Yu-Chi Tu, Pan Gao, Qian-Qian Liao, Peng Zhou, Hui Zhang, Hua-Pan Shu, Lu-Lu Sun, Li Feng, Li-Jun Yao.
Theranostics 2024 Jan; 14(2):861.
Application:IHC, Mouse, Aorta, Arteriovenous fistula.
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Lack of serum- and glucocorticoid-inducible kinase 3 leads to podocyte dysfunction.
Peng LQ, Zhao H, Liu S, Yuan YP, Yuan CY, Mwamunyi MJ, Pearce D, Yao LJ.
FASEB Journal 2017 Sep; [Epub].
Application:WB-Ce, Mouse, Mouse podocytes.
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SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
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