PDE8B polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human thyroid with PDE8B polyclonal antibody (Cat # PAB16426).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDE8B.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human PDE8B.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
Internal domain of human.
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human thyroid with PDE8B polyclonal antibody (Cat # PAB16426). -
Gene Info — PDE8B
Entrez GeneID
8622Protein Accession#
O95263Gene Name
PDE8B
Gene Alias
FLJ11212, PPNAD3
Gene Description
phosphodiesterase 8B
Omim ID
603390Gene Ontology
HyperlinkGene Summary
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5-prime,3-prime-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been grouped into several families based on substrate affinities, inhibitor sensitivities, mode of regulation, and amino acid sequence homologies. The PDE8 family contains high-affinity cAMP-specific, IBMX (3-isobutyl-1-methyl-xanthine)-insensitive PDEs, such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that presumably accounts for the distinctive regulatory properties unique to the individual families.[supplied by OMIM
Other Designations
3',5' cyclic nucleotide phosphodiesterase 8B
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Interactome
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