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Last updated: 2017/12/10
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PDE8B polyclonal antibody

  • Catalog # : PAB16425
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PDE8B.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to human PDE8B.
  • Host:
  • Rabbit
  • Reactivity:
  • Horse, Human, Monkey
  • Specificity:
  • Internal domain of human.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human thyroid with PDE8B polyclonal antibody (Cat # PAB16425).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 8622
  • Gene Name:
  • PDE8B
  • Gene Alias:
  • FLJ11212,PPNAD3
  • Gene Description:
  • phosphodiesterase 8B
  • Gene Summary:
  • Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5-prime,3-prime-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been grouped into several families based on substrate affinities, inhibitor sensitivities, mode of regulation, and amino acid sequence homologies. The PDE8 family contains high-affinity cAMP-specific, IBMX (3-isobutyl-1-methyl-xanthine)-insensitive PDEs, such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that presumably accounts for the distinctive regulatory properties unique to the individual families.[supplied by OMIM
  • Other Designations:
  • 3',5' cyclic nucleotide phosphodiesterase 8B
  • Gene Pathway
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