ADRA1B polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human smooth muscle cells with ADRA1B polyclonal antibody (Cat # PAB16419).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human ADRA1B.
Host
Rabbit
Reactivity
Human
Specificity
C-terminal Cytoplasmic domain of human.
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human smooth muscle cells with ADRA1B polyclonal antibody (Cat # PAB16419). -
Gene Info — ADRA1B
Entrez GeneID
147Protein Accession#
P35368Gene Name
ADRA1B
Gene Alias
ADRA1, ALPHA1BAR
Gene Description
adrenergic, alpha-1B-, receptor
Omim ID
104220Gene Ontology
HyperlinkGene Summary
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq
Other Designations
alpha-1B-adrenergic receptor
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Interactome
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Pathway
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Disease
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