FZD7 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FZD7.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human FZD7.
Host
Rabbit
Reactivity
Bovine, Dog, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Specificity
C-terminal domain of human.
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human heart with FZD7 polyclonal antibody (Cat # PAB16379). -
Gene Info — FZD7
Entrez GeneID
8324Protein Accession#
O75084Gene Name
FZD7
Gene Alias
FzE3
Gene Description
frizzled homolog 7 (Drosophila)
Omim ID
603410Gene Ontology
HyperlinkGene Summary
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq
Other Designations
Frizzled, drosophila, homolog of, 7|frizzled 7
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