PDPN polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PDPN.
Immunogen
A synthetic peptide corresponding to amino acids at internal region human PDPN.
Sequence
C-EKVDGDTQTTVEKD
Host
Goat
Theoretical MW (kDa)
24.9, 24.7, 12.4, 12
Reactivity
Human
Specificity
This antibody is expected to recognize all isoforms (NP_006465.3; NP_938203.2; NP_001006625.1; NP_001006626.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PDPN
Entrez GeneID
10630Protein Accession#
NP_006465.3;NP_938203.2;NP_001006625.1;NP_001006626.1Gene Name
PDPN
Gene Alias
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2
Gene Description
podoplanin
Omim ID
608863Gene Ontology
HyperlinkGene Summary
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000009640|OTTHUMP00000044504|glycoprotein, 36-KD|hT1alpha-1|hT1alpha-2|lung type I cell membrane associated glycoprotein|lung type-I cell membrane-associated glycoprotein|lung type-I cell membrane-associated glycoprotein (T1A-2)
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Interactome
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Disease
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Publication Reference
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Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis.
Oakley GJ, Fuhrer K, Seethala RR.
Modern Pathology 2008 Dec; 21(12):1461.
Application：IHC-P, Human, Human chordoma, rhabdoid chordoma.
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Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis.
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