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Last updated: 2016/12/4
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CCR3 polyclonal antibody

  • Catalog # : PAB16207
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR3.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to human CCR3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • 3rd extracellular domain of human .
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in lymphocytes from human tonsil with CCR3 polyclonal antibody (Cat # PAB16207).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1232
  • Gene Name:
  • CCR3
  • Gene Alias:
  • CC-CKR-3,CD193,CKR3,CMKBR3,MGC102841
  • Gene Description:
  • chemokine (C-C motif) receptor 3
  • Gene Summary:
  • The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • CC chemokine receptor 3,OTTHUMP00000164718,b-chemokine receptor,eosinophil CC chemokine receptor 3,eosinophil eotaxin receptor
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