CCR10 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CCR10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human CCR10.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
N-terminal domain of human. Predicted crossreactivity with mouse due to sequence similarity .
Form
Liquid
Purification
Immunoaffinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining of human capillaries of skin with CCR10 polyclonal antibody (Cat # PAB16200). -
Gene Info — CCR10
Entrez GeneID
2826Protein Accession#
P46092Gene Name
CCR10
Gene Alias
GPR2
Gene Description
chemokine (C-C motif) receptor 10
Omim ID
600240Gene Ontology
HyperlinkGene Summary
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM
Other Designations
CC chemokine receptor 10|G protein-coupled receptor 2
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Interactome
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Pathway
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