MEF2D (phospho S180) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MEF2D.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S180 of human MEF2D.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
ELISA (1:2000-1:5000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — MEF2D
Entrez GeneID
4209Gene Name
MEF2D
Gene Alias
DKFZp686I1536
Gene Description
myocyte enhancer factor 2D
Omim ID
600663Gene Ontology
HyperlinkGene Summary
polypeptide D (myocyte enhancer factor 2D)|MEF2D/DAZAP1 fusion|OTTHUMP00000031810|myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein
Other Designations
MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)|MEF2D/DAZAP1 fusion|OTTHUMP00000031810|myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein
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Interactome
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Disease
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Publication Reference
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Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma.
Wenjuan Ma, Yanling Wang, Rongxin Zhang, Fan Yang, Duo Zhang, Menggui Huang, Lin Zhang, Jay F. Dorsey, Zev A. Binder, Donald M. O’Rourke, Joseph A. Fraietta, Yanqing Gong and Yi Fan.
Nature Cancer 2021 Jan; 2(1):83.
Application:WB-Ce, Human, Human glioblastoma cells.
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Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP.
PNAS 2004 Aug; 101(33):12130.
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Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis.
Gong X, Tang X, Wiedmann M, Wang X, Peng J, Zheng D, Blair LA, Marshall J, Mao Z.
Neuron 2003 Apr; 38(1):33.
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Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.
Okamoto S, Li Z, Ju C, Scholzke MN, Mathews E, Cui J, Salvesen GS, Bossy-Wetzel E, Lipton SA.
PNAS 2002 Mar; 99(6):3974.
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Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma.
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