BCAR1 (phospho S639) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCAR1.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S639 of human BCAR1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:2000-1:5000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — BCAR1
Entrez GeneID
9564Gene Name
BCAR1
Gene Alias
CAS, CAS1, CASS1, CRKAS, P130Cas
Gene Description
breast cancer anti-estrogen resistance 1
Omim ID
602941Gene Ontology
HyperlinkGene Summary
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM
Other Designations
Cas scaffolding protein family member 1|Crk-associated substrate p130Cas
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Interactome
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Pathway
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Disease
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Publication Reference
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A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP.
PNAS 2008 Jul; 105(31):10762.
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The consensus coding sequences of human breast and colorectal cancers.
Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.
Science 2006 Sep; 314(5797):268.
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A quantitative atlas of mitotic phosphorylation.
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