Products

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

Protein Accession#

Gene Name

PPP2R3A

Gene Alias

PPP2R3, PR130, PR72

Gene Description

protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha

Omim ID

Gene Ontology

Gene Summary

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Other Designations

PP2A, subunit B, B''-PR72/PR130|PP2A, subunit B, B72/B130 isoforms|PP2A, subunit B, R3 isoform|Serine/threonine protein phosphatase 2A, 72/130 kDa regulatory subunit B|protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and