MTNR1B polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of MTNR1B.
Immunogen
A synthetic peptide corresponding to C-terminus of human MTNR1B.
Sequence
C-QDASKGSHAEGLQSP
Host
Goat
Theoretical MW (kDa)
40.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
MTNR1B polyclonal antibody (Cat # PAB15648) (3.8 ug/mL) staining of paraffin embedded human cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MTNR1B
Entrez GeneID
4544Protein Accession#
NP_005950.1Gene Name
MTNR1B
Gene Alias
MEL-1B-R, MT2
Gene Description
melatonin receptor 1B
Omim ID
600804Gene Ontology
HyperlinkGene Summary
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq
Other Designations
melatonin receptor MEL1B|melatonin receptor type 1B
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Interactome
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Pathway
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Disease
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Publication Reference
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Melatonin suppresses nighttime memory formation in zebrafish.
Rawashdeh O, de Borsetti NH, Roman G, Cahill GM.
Science 2007 Nov; 318(5853):1144.
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Melatonin suppresses nighttime memory formation in zebrafish.
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