KCNMA1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of KCNMA1.
Immunogen
A synthetic peptide corresponding to human KCNMA1.
Sequence
C-RESRDKQNRKEMVYR
Host
Goat
Theoretical MW (kDa)
132,
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — KCNMA1
Entrez GeneID
3778Protein Accession#
NP_001014797.1Gene Name
KCNMA1
Gene Alias
BKTM, DKFZp686K1437, KCa1.1, MGC71881, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, mSLO1
Gene Description
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
BKCA alpha subunit|Drosophila slowpoke-like|OTTHUMP00000019904|OTTHUMP00000060198|OTTHUMP00000064154|OTTHUMP00000064155|OTTHUMP00000064156|OTTHUMP00000064157|OTTHUMP00000064158|OTTHUMP00000064159|OTTHUMP00000064160|OTTHUMP00000064161|OTTHUMP00000064162|OT
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Interactome
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Pathway
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Disease
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Publication Reference
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Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment.
Yuan C, O'Connell RJ, Wilson A, Pietrzykowski AZ, Treistman SN.
The Journal of Biological Chemistry 2008 Feb; 283(8):5090.
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Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment.
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