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Last updated: 2016/11/27
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KCNJ1 polyclonal antibody

  • Catalog # : PAB15638
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised aganist synthetic peptide of KCNJ1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human KCNJ1.
  • Sequence:
  • C-DQININFVVDAGNEN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 44.8, 42.7
  • Reactivity:
  • Human
  • Specificity:
  • Approximately 45 KDa band observed in human, mouse and rat kidney lysates (calculated MW of 44.8 KDa according to NP_000211.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • KCNJ1 polyclonal antibody (Cat # PAB15638) (1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3758
  • Gene Name:
  • KCNJ1
  • Gene Alias:
  • KIR1.1,ROMK,ROMK1
  • Gene Description:
  • potassium inwardly-rectifying channel, subfamily J, member 1
  • Gene Summary:
  • Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ATP-regulated potassium channel ROM-K,ATP-sensitive inward rectifier potassium channel 1,OTTHUMP00000045938,inwardly rectifying K+ channel,potassium inwardly-rectifying channel J1
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