JAM2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of JAM2.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human JAM2.
Sequence
C-NPRLGSQSTNSSYT
Host
Goat
Theoretical MW (kDa)
33.2
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — JAM2
Entrez GeneID
58494Protein Accession#
NP_067042.1Gene Name
JAM2
Gene Alias
C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Gene Description
junctional adhesion molecule 2
Omim ID
606870Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq
Other Designations
JAM-IT/VE-JAM|OTTHUMP00000096100|junctional adhesion molecule B|vascular endothelial junction-associated molecule
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Interactome
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Pathway
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Publication Reference
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Molecular identification of a retinal cell type that responds to upward motion.
Kim IJ, Zhang Y, Yamagata M, Meister M, Sanes JR.
Nature 2008 Mar; 452(7186):478.
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Molecular identification of a retinal cell type that responds to upward motion.
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