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Last updated: 2016/12/4
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HAMP polyclonal antibody

  • Catalog # : PAB15632
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised aganist synthetic peptide of HAMP.
  • Immunogen:
  • A synthetic peptide corresponding to human HAMP.
  • Sequence:
  • TSGSVFPQQTGQLAE-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 9.41
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • HAMP
  • Gene Alias:
  • HEPC,HEPCIDIN,HFE2B,LEAP-1,LEAP1,PLTR
  • Gene Description:
  • hepcidin antimicrobial peptide
  • Gene Summary:
  • The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
  • Other Designations:
  • liver-expressed antimicrobial peptide,putative liver tumor regressor
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