GABRB2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of GABRB2.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human GABRB2.
Sequence
C-HSFGRNALERHVAQ
Host
Goat
Theoretical MW (kDa)
59.2, 54.6
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GABRB2
Entrez GeneID
2561Protein Accession#
NP_068711.1Gene Name
GABRB2
Gene Alias
MGC119386, MGC119388, MGC119389
Gene Description
gamma-aminobutyric acid (GABA) A receptor, beta 2
Omim ID
600232Gene Ontology
HyperlinkGene Summary
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq
Other Designations
OTTHUMP00000160872
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Interactome
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Pathway
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Disease
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Publication Reference
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Association of SNPs and haplotypes in GABAA receptor beta2 gene with schizophrenia.
Lo WS, Lau CF, Xuan Z, Chan CF, Feng GY, He L, Cao ZC, Liu H, Luan QM, Xue H.
Molecular Psychiatry 2004 Jun; 9(6):603.
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Association of SNPs and haplotypes in GABAA receptor beta2 gene with schizophrenia.
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