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Last updated: 2016/10/23
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CHRFAM7A polyclonal antibody

  • Catalog # : PAB15617
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised aganist synthetic peptide of CHRFAM7A.
  • Immunogen:
  • A synthetic peptide corresponding to human CHRFAM7A.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 46.2, 35.5
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Application Image
  • Gene Information
  • Gene Name:
  • Gene Alias:
  • CHRNA7,CHRNA7-DR1,D-10,MGC120482,MGC120483
  • Gene Description:
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
  • Gene Summary:
  • The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq
  • Other Designations:
  • CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion,CHRNA7-FAM7A fusion,alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid,alpha-7 nicotinic cholinergic rec
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