ATG4D polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of ATG4D.
Immunogen
A synthetic peptide corresponding to near human ATG4D.
Sequence
CSQLAQPTLRLPRT
Host
Goat
Theoretical MW (kDa)
52.9
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ATG4D
Entrez GeneID
84971Protein Accession#
NP_116274.3Gene Name
ATG4D
Gene Alias
APG4-D, APG4D, AUTL4
Gene Description
ATG4 autophagy related 4 homolog D (S. cerevisiae)
Omim ID
611340Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog D|AUT-like 4, cysteine endopeptidase|autophagin-4|autophagy-related cysteine endopeptidase 4|cysteine protease involved in autophagy
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Pathway
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Publication Reference
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Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.
Marino G, Uria JA, Puente XS, Quesada V, Bordallo J, Lopez-Otin C.
The Journal of Biological Chemistry 2002 Nov; 278(6):3671.
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Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.
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