ARG1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of ARG1.
Immunogen
A synthetic peptide corresponding to human ARG1.
Sequence
CFGLAREGNHKPID
Host
Goat
Theoretical MW (kDa)
34.7
Reactivity
Human
Specificity
Approximately 37 KDa band observed in human liver lysates (calculated MW of 34.7 KDa according to NP_000036.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ARG1 polyclonal antibody (Cat # PAB15607) (0.01 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ARG1
Entrez GeneID
383Protein Accession#
NP_000036.2Gene Name
ARG1
Gene Alias
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Gene Description
arginase, liver
Gene Ontology
HyperlinkGene Summary
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq
Other Designations
A-I|OTTHUMP00000017209|arginase, type I
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Interactome
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Pathway
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Disease
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Publication Reference
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A review of asthma genetics: gene expression studies and recent candidates.
Malerba G, Pignatti PF.
J Appl Genet 2005 Jan; 46(1):93.
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A review of asthma genetics: gene expression studies and recent candidates.
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