AGXT polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of AGXT.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human AGXT.
Sequence
C-DKAKKKMYSRK
Host
Goat
Theoretical MW (kDa)
43
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — AGXT
Entrez GeneID
189Protein Accession#
NP_000021.1Gene Name
AGXT
Gene Alias
AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6
Gene Description
alanine-glyoxylate aminotransferase
Gene Ontology
HyperlinkGene Summary
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq
Other Designations
L-alanine: glyoxylate aminotransferase 1|hepatic peroxisomal alanine:glyoxylate aminotransferase|serine-pyruvate aminotransferase|serine:pyruvate aminotransferase
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Interactome
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Pathway
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Disease
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Publication Reference
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Molecular etiology of primary hyperoxaluria type 1: new directions for treatment.
Danpure CJ.
American Journal of Nephrology 2005 May; 25(3):303.
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Molecular etiology of primary hyperoxaluria type 1: new directions for treatment.
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