ADAM23 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of ADAM23.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human ADAM23.
Sequence
NGKPQYSKGGEHC
Host
Goat
Theoretical MW (kDa)
91.9
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADAM23
Entrez GeneID
8745Protein Accession#
NP_003803.1Gene Name
ADAM23
Gene Alias
MDC3
Gene Description
ADAM metallopeptidase domain 23
Omim ID
603710Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. [provided by RefSeq
Other Designations
a disintegrin and metalloproteinase domain 23
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Interactome
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Disease
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Publication Reference
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ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation.
Takada H, Imoto I, Tsuda H, Nakanishi Y, Ichikura T, Mochizuki H, Mitsufuji S, Hosoda F, Hirohashi S, Ohki M, Inazawa J.
Oncogene 2005 Dec; 24(54):8051.
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ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation.
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