NOS2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NOS2.
Immunogen
A synthetic peptide corresponding to C-terminus of human NOS2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
The human iNOS sequence used has high homology with similar regions in rat and mouse iNOS.
Form
Liquid
Recommend Usage
ELISA (1:4000)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of mouse macrophages untreated (Lane 1) or treated (Lane 2) with IFNg (10 ng/ml) and LPS (1mg/ml) for 12 hr (20 mg/lane). Blots were probed withNOS2 polyclonal antibody (Cat # PAB15600 ; 1 : 2000).Enzyme-linked Immunoabsorbent Assay
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Gene Info — NOS2
Entrez GeneID
4843GeneBank Accession#
P35228Gene Name
NOS2
Gene Alias
HEP-NOS, INOS, NOS, NOS2A
Gene Description
nitric oxide synthase 2, inducible
Gene Ontology
HyperlinkGene Summary
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
NOS, type II|nitric oxide synthase 2A|nitric oxide synthase 2A (inducible, hepatocytes)|nitric oxide synthase, macrophage
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Albuminuria
- Alzheimer disease
- Anemia
- Angina
- Angina Pectoris
- Arthritis
- Asthma
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