EDIL3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EDIL3.
Immunogen
A synthetic peptide corresponding to amino acids 200-350 of human EDIL3.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
100% sequence identity with human protein, 94% sequence with mouse protein. This antibody is useful for Western blot analysis where a band can be seen at ~53 KDa.
Form
Liquid
Recommend Usage
Immunocytochemistry (1:100)
Immunofluorescence (1:100)
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (30% glycerol, 0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot with EDIL3 polyclonal antibody (Cat # PAB15527).
Lane 1 : normal human brain
Lane 2 : normal mouse brain.Immunocytochemistry
Immunofluorescence
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Gene Info — EDIL3
Entrez GeneID
10085Protein Accession#
O43854Gene Name
EDIL3
Gene Alias
DEL1, MGC26287
Gene Description
EGF-like repeats and discoidin I-like domains 3
Omim ID
606018Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior. [provided by RefSeq
Other Designations
EGF-like repeats and discoidin I-like domains-containing protein 3|developmental endothelial locus-1
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Interactome
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Disease
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Publication Reference
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Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer.
Zou X, Qiao H, Jiang X, Dong X, Jiang H, Sun X.
Journal of Biomedical Science 2008 Dec; 16(1):33.
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Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.
Choi EY, Chavakis E, Czabanka MA, Langer HF, Fraemohs L, Economopoulou M, Kundu RK, Orlandi A, Zheng YY, Prieto DA, Ballantyne CM, Constant SL, Aird WC, Papayannopoulou T, Gahmberg CG, Udey MC, Vajkoczy P, Quertermous T, Dimmeler S, Weber C, Chavakis T.
Science 2008 Nov; 322(5904):1101.
Application:Func, Mouse, Mouse neutrophils.
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Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer.
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