PDK4 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot of human heart tissue lysate with PDK4 polyclonal antibody (Cat # PAB15513).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDK4.
Immunogen
A synthetic peptide corresponding to amino acids 200-250 of human PDK4.
Host
Rabbit
Reactivity
Human, Rat
Specificity
Immunogen has 94% homology with rat and 88% homology with mouse. This antibody is useful for Western blot, where a band is seen ~49 KDa.
Form
Liquid
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (30% glycerol, 0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot of human heart tissue lysate with PDK4 polyclonal antibody (Cat # PAB15513). -
Gene Info — PDK4
Entrez GeneID
5166Protein Accession#
Q16654Gene Name
PDK4
Gene Alias
FLJ40832
Gene Description
pyruvate dehydrogenase kinase, isozyme 4
Omim ID
602527Gene Ontology
HyperlinkGene Summary
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq
Other Designations
pyruvate dehydrogenase kinase 4|pyruvate dehydrogenase kinase, isoenzyme 4
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