HSPE1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HSPE1.
Immunogen
A synthetic peptide corresponding to amino acids 91-101 of human HSPE1.
Host
Rabbit
Reactivity
Bovine, Dog, Frog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Sheep
Specificity
Detects ~ 10KDa.
Form
Liquid
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of rat brain extracts with HSPE1 polyclonal antibody (Cat # PAB15431).Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — HSPE1
Entrez GeneID
3336Gene Name
HSPE1
Gene Alias
CPN10, GROES, HSP10
Gene Description
heat shock 10kDa protein 1 (chaperonin 10)
Omim ID
600141Gene Ontology
HyperlinkGene Summary
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. [provided by RefSeq
Other Designations
chaperonin 10|heat shock 10kD protein 1 (chaperonin 10)|heat shock 10kDa protein 1
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Interactome
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Disease
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Publication Reference
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An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space.
Bie AS, Cömert C, Körner R, Corydon TJ, Palmfeldt J, Hipp MS, Hartl FU, Bross P.
Cell Stress & Chaperones 2020 May; 25(3):407.
Application:IP, WB-Tr, Human, HEK 293 cells.
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The purification of early-pregnancy factor to homogeneity from human platelets and identification as chaperonin 10.
Cavanagh AC, Morton H.
European Journal of Biochemistry 1994 Jun; 222(2):551.
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Immunosuppression detected in pregnant mice by rosette inhibition test.
Morton H, Hegh V, Clunie GJ.
Nature 1974 May; 249(456):459.
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An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space.
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