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Last updated: 2019/12/1

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PDK1 polyclonal antibody (DyLight 650) 

  • Catalog # : PAB15330
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PDK1.
  • Immunogen:
  • A synthetic peptide corresponding to residues within 350-436 at C-terminu of human PDK1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • By Western blot a band is seen at ~49 kDa, representing PDK1 protein. There are also two higher and one lower non-specific molecular weight bands. In ICC/IF, mitochondiral staining was observed in HeLa cells. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
  • Form:
  • Liquid
  • Conjugation:
  • DyLight 650
  • Purification:
  • Immunogen affinity purification
  • Recommend Usage:
  • Immunocytochemistry/Immunofluorescence
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium borate (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 5163
  • Gene Name:
  • PDK1
  • Gene Alias:
  • -
  • Gene Description:
  • pyruvate dehydrogenase kinase, isozyme 1
  • Gene Summary:
  • Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. [provided by RefSeq
  • Other Designations:
  • mitochondrial pyruvate dehydrogenase kinase isoenzyme 1,pyruvate dehydrogenase kinase, isoenzyme 1
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