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Last updated: 2019/8/18
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SREBF1 polyclonal antibody (DyLight 650) 

  • Catalog # : PAB15198
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SREBF1.
  • Immunogen:
  • A synthetic peptide corresponding to residues within 700-800 of human SREBF1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody is useful for Western blot, where a band is seen at ~65 kDa (mature form). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
  • Form:
  • Liquid
  • Conjugation:
  • DyLight 650
  • Purification:
  • Immunogen affinity purification
  • Recommend Usage:
  • Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium borate (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 6720
  • Gene Name:
  • SREBF1
  • Gene Alias:
  • SREBP-1c,SREBP1,bHLHd1
  • Gene Description:
  • sterol regulatory element binding transcription factor 1
  • Gene Summary:
  • This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • sterol regulatory element binding protein-1
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