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Last updated: 2019/8/18
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BIRC5 (phospho S20) polyclonal antibody (DyLight 650) 

  • Catalog # : PAB15179
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of BIRC5.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S20 of human BIRC5.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen at ~16.5 kDa. In ICC/IF staining was observed in the spindle midzone, centrosome and intercellular bridge. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
  • Form:
  • Liquid
  • Conjugation:
  • DyLight 650
  • Purification:
  • Immunogen affinity purification
  • Recommend Usage:
  • Immunocytochemistry/Immunofluorescence
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium borate (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 332
  • Gene Name:
  • BIRC5
  • Gene Alias:
  • API4,EPR-1
  • Gene Description:
  • baculoviral IAP repeat-containing 5
  • Gene Summary:
  • This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
  • Other Designations:
  • apoptosis inhibitor 4,baculoviral IAP repeat-containing protein 5,survivin variant 3 alpha
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