TMED10 polyclonal antibody (DyLight 550)
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TMED10.
Immunogen
A synthetic peptide corresponding to amino acids 50-150 of human TMED10.
Host
Rabbit
Reactivity
Bovine, Human, Mouse, Primates, Rabbit, Rat, Xenopus
Specificity
TMP21 This antibody is useful for Western blot analysis where a band is seen at ~21 KDa.
Form
Liquid
Conjugation
DyLight 550
Purification
Immunogen affinity purification
Recommend Usage
Western Blot (2 ug/mL)
Immunohistochemistry (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium borate (0.05% sodium azide).
Storage Instruction
Store at 4°C in the dark.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
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Gene Info — TMED10
Entrez GeneID
10972Protein Accession#
P49755Gene Name
TMED10
Gene Alias
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I
Gene Description
transmembrane emp24-like trafficking protein 10 (yeast)
Omim ID
605406Gene Ontology
HyperlinkGene Summary
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq
Other Designations
21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10
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Interactome
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Disease
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