TMED10 polyclonal antibody (DyLight 650)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TMED10.
Immunogen
A synthetic peptide corresponding to residues within 50-150 at internal region of human TMED10.
Host
Rabbit
Reactivity
Bovine, Human, Mouse, Primates, Rabbit, Rat, Xenopus
Specificity
This antibody is useful for Western blot analysis where a band is seen at ~21 KDa.
Form
Liquid
Conjugation
DyLight 650
Purification
Immunogen affinity purification
Recommend Usage
Immunohistochemistry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium borate (0.05% sodium azide).
Storage Instruction
Store at 4°C in the dark.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
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Gene Info — TMED10
Entrez GeneID
10972Protein Accession#
P49755Gene Name
TMED10
Gene Alias
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I
Gene Description
transmembrane emp24-like trafficking protein 10 (yeast)
Omim ID
605406Gene Ontology
HyperlinkGene Summary
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq
Other Designations
21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10
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Interactome
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Disease
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