TMED10 polyclonal antibody (HRP)
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TMED10.
Immunogen
A synthetic peptide corresponding to amino acids 100-200 of human TMED10.
Host
Rabbit
Reactivity
Bovine, Human, Mouse, Primates, Rabbit, Rat
Specificity
This antibody is useful for Western blot analysis where a band is seen at ~21 KDa.
Form
Liquid
Conjugation
HRP
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C. Do not freeze.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — TMED10
Entrez GeneID
10972Protein Accession#
P49755Gene Name
TMED10
Gene Alias
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I
Gene Description
transmembrane emp24-like trafficking protein 10 (yeast)
Omim ID
605406Gene Ontology
HyperlinkGene Summary
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq
Other Designations
21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10
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Disease
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