KCNK2 polyclonal antibody (Biotin)
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KCNK2.
Immunogen
A synthetic peptide corresponding to amino acids 1-100 of human KCNK2.
Host
Rabbit
Reactivity
Human
Specificity
88% sequence identity with rat protein. TREK 1 Please note that it is essential to run against membrane preps. NOT recommended for immunohistochemistry.
Form
Liquid
Conjugation
Biotin
Recommend Usage
Western Blot (2 ug/ mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C. Do not freeze.
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Applications
Western Blot
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Gene Info — KCNK2
Entrez GeneID
3776Protein Accession#
O95069Gene Name
KCNK2
Gene Alias
K2p2.1, MGC126742, MGC126744, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e
Gene Description
potassium channel, subfamily K, member 2
Omim ID
603219Gene Ontology
HyperlinkGene Summary
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
K2P2.1 potassium channel|OTTHUMP00000035062|OTTHUMP00000035063|TWIK-related potassium channel 1|potassium inwardly-rectifying channel, subfamily K, member 2|tandem-pore-domain potassium channel TREK-1|two-pore potassium channel 1
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Disease
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