Rabbit polyclonal antibody raised against synthetic peptide of WNK4.
A synthetic peptide corresponding to amino acids 200-300 of human WNK4.
Human, Mouse, Rat
This antibody can be used to detect mouse and human (very weakly) WNK4 protein. NB600-284 is specific to WNK4 protein. This antibody is useful for Western blot where a band is seen at ~135-155 kD. No other applications have been tested.
Western Blot (2 ug/ mL) The optimal working dilution should be determined by the end user.
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB