SERPINF1/SERPINF2 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against SERPINF1/SERPINF2.
Immunogen
Purified human SERPINF1/SERPINF2.
Host
Sheep
Reactivity
Human
Specificity
This antibody has a single antigen reactivity with minimal cross reactivity with other human serum proteins.
Form
Liquid
Recommend Usage
ELISA (1:1000)
Immunodiffusion (1:32)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunocytochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
Immunodiffusion
Immunoelectron Microscopy
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Gene Info — SERPINF1
Entrez GeneID
5176Gene Name
SERPINF1
Gene Alias
EPC-1, PEDF, PIG35
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Omim ID
172860Gene Ontology
HyperlinkGene Summary
The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.[supplied by OMIM
Other Designations
pigment epithelium-derived factor|proliferation-inducing protein 35|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
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Gene Info — SERPINF2
Entrez GeneID
5345Gene Name
SERPINF2
Gene Alias
A2AP, AAP, ALPHA-2-PI, API, PLI
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Omim ID
262850Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
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Interactome
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Pathway
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Disease
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