CAPG polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blotting of human fibroblast extract with CAPG polyclonal antibody (Cat # PAB14870).
Dr. Yutsudo, MAt Research Institute for Microbial Diseases, Osaka University Japan.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CAPG.
Immunogen
Recombinant GST fusion protein corresponding to human CAPG.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2% Block Ace)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blotting of human fibroblast extract with CAPG polyclonal antibody (Cat # PAB14870).
Dr. Yutsudo, MAt Research Institute for Microbial Diseases, Osaka University Japan. -
Gene Info — CAPG
Entrez GeneID
822Gene Name
CAPG
Gene Alias
AFCP, MCP
Gene Description
capping protein (actin filament), gelsolin-like
Omim ID
153615Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq
Other Designations
actin-regulatory protein CAP-G|gelsolin-like capping protein|macrophage capping protein
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Interactome
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Disease
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Publication Reference
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Cap G, a gelsolin family protein modulating protective effects of unidirectional shear stress.
Pellieux C, Desgeorges A, Pigeon CH, Chambaz C, Yin H, Hayoz D, Silacci P.
The Journal of Biological Chemistry 2003 Aug; 278(31):29136.
Application：WB-Tr, Bovine, Bovine aorta endothelial cells.
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Comparisons of CapG and gelsolin-null macrophages: demonstration of a unique role for CapG in receptor-mediated ruffling, phagocytosis, and vesicle rocketing.
Witke W, Li W, Kwiatkowski DJ, Southwick FS.
International Journal of Cell Biology 2001 Aug; 154(4):775.
Application：WB-Ce, WB-Ti, Mouse, Hearts, Lungs, Spleen, Thymus, Macrophages.
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Molecular cloning of human macrophage capping protein cDNA. A unique member of the gelsolin/villin family expressed primarily in macrophages.
Dabiri GA, Young CL, Rosenbloom J, Southwick FS.
The Journal of Biological Chemistry 1992 Aug; 267(23):16545.
Application：WB-Ce, WB-Ti, Rabbit, Rabbit macrophages, Rabbit tissues.
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Cap G, a gelsolin family protein modulating protective effects of unidirectional shear stress.
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