RPS19 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Detecting RPS19 protein in HepG2 cell homogenate.
Lane 1 : Non immuned rabbit antibody.
Lane 2 : RPS19 polyclonal antibody (Cat # PAB14867).
Enzyme-linked Immunoabsorbent Assay
Reactivity in ELISA.
a : Non immuned rabbit antibody.
b : RPS19 polyclonal antibody (Cat # PAB14867).
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RPS19.
Immunogen
Recombinant protein corresponding to human RPS19.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2% Block Ace)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Detecting RPS19 protein in HepG2 cell homogenate.
Lane 1 : Non immuned rabbit antibody.
Lane 2 : RPS19 polyclonal antibody (Cat # PAB14867).Enzyme-linked Immunoabsorbent Assay
Reactivity in ELISA.
a : Non immuned rabbit antibody.
b : RPS19 polyclonal antibody (Cat # PAB14867). -
Gene Info — RPS19
Entrez GeneID
6223Gene Name
RPS19
Gene Alias
DBA
Gene Description
ribosomal protein S19
Gene Ontology
HyperlinkGene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq
Other Designations
40S ribosomal protein S19|Diamond-Blackfan anemia
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Interactome
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Pathway
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Disease
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Publication Reference
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The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia.
Draptchinskaia N, Gustavsson P, Andersson B, Pettersson M, Willig TN, Dianzani I, Ball S, Tchernia G, Klar J, Matsson H, Tentler D, Mohandas N, Carlsson B, Dahl N.
Nature Genetics 1999 Feb; 21(2):169.
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A monocyte chemotactic factor, S19 ribosomal protein dimer, in phagocytic clearance of apoptotic cells.
Horino K, Nishiura H, Ohsako T, Shibuya Y, Hiraoka T, Kitamura N, Yamamoto T.
Lab Invest 1998 May; 78(5):603.
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Monocyte chemotactic factor in rheumatoid arthritis synovial tissue. Probably a cross-linked derivative of S19 ribosomal protein.
Nishiura H, Shibuya Y, Matsubara S, Tanase S, Kambara T, Yamamoto T.
The Journal of Biological Chemistry 1996 Jan; 271(2):878.
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The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia.
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